Cct036477
WebDescription: CCT036477 is a selective inhibitor of wingless-type MMTV integration site family (WNT)-dependent transcription. It reduces the transcriptional activity of the T-cell … WebCCT036477: Catalog Number: M8243: CAS Number: 305372-78-5: 1.2 Relevant identified uses of the substance or mixture and uses advised against; Identified uses: For research use only, not for human or veterinary use. 1.3 Details of the supplier of the safety data sheet; Company: Abmole Bioscience Inc. 8300 Cypress Creek Parkway, Suite 450 Houston ...
Cct036477
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WebEfficiently mine multiple large-scale pharmacogenomic datasets. WebCCT036477 (α-(4-Chlorophenyl)-2-methyl-N-2-pyridinyl-1H-indole-3-methanamine); ≥ 98% HPLC; Wnt β-catenin antagonist; CCT036477 is an inhibitor of Wnt signaling; HR EN Applications Products Services Support
WebCCT036477, iCRT14, or PKF118-310 preferentially eliminated the MCL-ICs. Conclusions: Our results suggest that Wnt signaling is critical for the maintenance and survival of MCL … WebCCT036477 is an inhibitor of Wnt signaling. It does not alter β-catenin levels but blocks transcription at the β-catenin level. CCT036477 inhibited growth in several cancer cell lines and showed clear activity in vivo, blocking development of Zebrafish and Xenopus embryos and expression of Wnt target genes.
WebJun 4, 2024 · Further analysis by the GSCALite website revealed that the methylation of HOXB3/5/6/8 in ccRCC was significantly negatively correlated to gene expression, while HOXB5/9 was positively correlated to the CCT036477 drug target. WebCCT036477 is an inhibitor of Wnt signaling and growth in several cancer lines. Studies show that CCT036477 does not alter β-catenin levels but blocks transcription at the β-catenin …
Wnt Pathway Inhibitor XI, CCT036477 - CAS 305372-78-5 - Calbiochem. Download. Zoom. The Wnt Pathway Inhibitor XI, CCT036477, also referenced under CAS 305372-78-5, controls the biological activity of Wnt Pathway. This small molecule/inhibitor is primarily used for Cancer applications.
Web名称：西红花苷I 42553-65-1 仅供体外科研实验研究使用，不得用于其他用途! 产品详情请点击在线咨询，咨询在线客服。 上海韵泰(Yun Tai ）是一家领先的化学、生命科学和材料科学、仪器设备等领域研发试剂的制造、销售商，我们的产品在基础科学领域得到广泛的应用,我 … dr robertshaw urologistWebView or download the Wnt Pathway Inhibitor XI, CCT036477 - CAS 305372-78-5 - Calbiochem MSDS (Material Safety Data Sheet) or SDS for 681674 from Merck. It … dr robertshaw cincinnatiWebFeb 14, 2013 · In vitro, the small molecule Wnt inhibitor CCT036477 induced a response within 4 h of treatment. By 7 days following doxycycline withdrawal, gene expression, cell proliferation and tissue morphology were undistinguishable from control animals.In conclusion, these results demonstrate that the reversal of Wnt signaling by inhibitors … collins brothers moving larchmontWebThe Current Procedural Terminology (CPT ®) code 26477 as maintained by American Medical Association, is a medical procedural code under the range - Repair, Revision, … collins brothers nashua nh soupWebCAS: 305372-78-5 Disrupts Wnt signaling collins brothers nashuaWebCCT036477 Preclinical: Actionable: In a preclinical study, CCT036477 inhibited Wnt pathway activation and growth of colorectal cancer cell lines harboring APC inactivating mutations in culture (PMID: 20610623). 20610623 APC inact mut colorectal cancer sensitive dr robert shaw fairfield ohioWebCCT036477, TRC-C227900-250MG, from Neurology. High-quality, certified reference materials, available to purchase online at LGC Standards. We use cookies to ensure that … dr robert shavelson tinton falls nj