WebDec 27, 2024 · Relevant to this, it has been recently demonstrated that in fibroblasts from a patient with SUCL deficiency, glutamine oxidation was impaired (Chinopoulos et al., 2024). The availability of α-ketoglutarate may occur either through the glutamate dehydrogenase (GLUD1) reaction or through the transamination reaction (DeBerardinis and Cheng, 2010). WebNov 5, 2014 · Christos Chinopoulos. Distribution Patterns of Astrocyte Populations in the Human Cortex. 05 August 2024. Shelley L. Forrest, Jordan Hanxi Kim, … Jillian J. Kril. Astrocytes display ultrastructural alterations and heterogeneity in the hippocampus of aged APP-PS1 mice and human post-mortem brain samples.
Cell-specific expression of key mitochondrial enzymes precludes …
WebMay 3, 2011 · Christos Chinopoulos, Which way does the citric acid cycle turn during hypoxia? The critical role of α‐ketoglutarate dehydrogenase complex, Journal of … WebOct 28, 2024 · The astrocyte-to-neuron lactate shuttle hypothesis entails that glycolytically derived pyruvate in astrocytes is converted to lactate instead of being catabolized in mitochondria. The mechanism of this metabolic rewiring is unclear. Here we show that astrocytes of the adult human neocortex and hippocampal formation do not express … tela ltn156at24-803
Gary Fiskum: H-index & Awards - Academic Profile Research.com
WebNeurobiology of Disease Mitochondrial -Ketoglutarate Dehydrogenase Complex Generates Reactive Oxygen Species Anatoly A. Starkov,1 Gary Fiskum,2 Christos Chinopoulos,2 Beverly J. Lorenzo,1 Susan E. Browne,1 Mulchand S. Patel,3 and M. Flint Beal1 1Department of Neurology and Neuroscience, Weill Medical College, Cornell … WebApr 8, 2016 · Christos Chinopoulos. Associate Professor; Semmelweis University; In this work, by expressing an NADH oxidase in the cytosolic or mitochondrial compartment of HeLa cells with a compromised electron transport chain (ETC), Titov et al make the point that NAD+ recycling is key for cell proliferation. Although their data provide irrefutable ... WebJan 3, 2014 · [email protected] Department of Medical Biochemistry, Hungarian Academy of Sciences, SE Laboratory for Neurobiochemistry, Semmelweis University, Budapest, Hungary Correspondence: Department of Medical Biochemistry, Semmelweis University, 37–47 Tuzolto Street, Budapest 1094, Hungary. telalux kcb