WebThe treatment of a non-union with growth factors like BMP-7 is an important part of the diamond concept. 6 Its osteoinductive effect as well as the increased bone healing has been described in former studies. 5 In addition to that, the results of our previous studies showed that local application of BMP-7 leads to a cytokine expression pattern ... Webbone to re-establish the disrupted continuity. It requires absolute contact of the fragments and almost complete stability and minimisation of the inter-fragmentary …
Enhancement of fracture healing with the diamond concept: the …
WebJun 29, 2016 · Intramembranous ossification is a problematic concept; there have been many studies of shaft healing that have also looked at membranous bone formation in shaft healing. ... Diamond et al. 2007, Aspenberg and Sandberg 2013, Chen et al. 2015), rather than mostly on the surfaces of old trabeculae—as previously thought. This appears very ... Web‘diamond concept’, a conceptual framework of what is essential for a successful bone healing response, has gained great acceptance for assessing and planning the management of fracture non-unions. logaritmische curve
The diamond concept--open questions - PubMed
WebSep 1, 2007 · The standard tissue engineering approach to provide solutions for impaired fracture healing, bone restoration and regeneration includes the utilisation of growth factors, scaffolds and mesenchymal stem cells (triangular concept). The ‘diamond concept’, being a conceptual framework for a successful bone repair response, gives equal importance to mechanical stability and the biological environment. Moreover, adequate bone vascularity and the physiological state of the host are thought to be essential within this framework of fracture … See more Risks of non-union can be defined as patient dependent and independent, as well as local and systemic, some of which can be modified to enhance fracture healing. A recent … See more A successful fracture healing response is dependent on the biological environment at the fracture site (availability of molecular mediators, progenitor … See more The concept of the biological chamber is based on the need for containment; For instance, where a long bone non-union case has been … See more WebTwo-step Masquelet-technique established a new procedure in the treatment of osseous defects, addressing prerequisites postulated by the “diamond concept”. Increase in blood perfusion and growth factors are enhanced by the “Masquelet-membrane”. To describe this, we measured serum levels of Vascular Endothelial Growth Factor (VEGF) of patients … logaritmische formule