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Hirsutanol a

Web26 mag 2024 · Among the new isolates, chondroterpene A (1) exhibited more significant NO production inhibitory activity in murine BV-2 microglial cells, and of all the isolated … Web30 nov 2024 · Objective: To assess whether miR-204 and HA affect A549 cell injury induced by lipopolysaccharide.Material and Methods.A549 cells were treated with hirsutanol A, and cell damage was induced by LPS followed by analysis of cell proliferation by CCK-8, cell apoptosis by flow cytometry, apoptosis-related protein expression by western blot, …

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Web25 giu 1998 · Hirsutanol A (6) and ent-gloeosteretriol (10) were found to be anti-microbial (Bacillus subtilus) active. All structures were elucidated by spectroscopic methods. Five … WebA new hirsutane sesquiterpenoid, hirsutanol E (1), together with the known compounds hirsutanol A (2) and hirsutanol F (3; gloeosteretriol) were obtained from AcOEt extract … rescare water treatment https://changesretreat.com

The Link of Marine Products with Autophagy-Associated Cell …

Web26 ago 2016 · Hirsutanol A—a potent anticancer agent isolated from marine fungal metabolites—was used as a positive control, and its cytotoxicities against the tested cancer cell lines are shown in Table 4. 4. Conclusions. The marine fungus Chondrostereum sp. was cultured in PD medium and afforded three new hirsutane-type sesquiterpenoids, ... Web10 ago 2024 · Hirsutanol A, a novel sesquiterpene compound from fungus Chondrostereum sp., induces apoptosis and inhibits tumor growth through mitochondrial-independent ROS production: Hirsutanol A inhibits tumor growth through ROS production [J]. Fen Yang, Wen-Dan Chen, Rong Deng, Journal of Translational Medicine . 2013,第1期 Web11 mag 2024 · Inhibition of p53 attenuates the effect of hirsutanol A on the apoptosis of Jurkat cells. Jurkat cells were treated with 5 µM hirsutanol A, 10 µM PFTα or 5 µM hirsutanol A + 10 µM PFTα for 48 h. rescare wichita kansas

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Category:Mir-204 Regulates LPS-Induced A549 Cell Damage by Targeting …

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Hirsutanol a

Absolute configurations of (−)-hirsutanol A and (−) …

Web8 feb 2013 · Background: Hirsutanol A is a novel sesquiterpene compound purified from fungus Chondrostereum sp. in Sarcophyton tortuosum. Our previous studies had … Web7 gen 2014 · 1. Introduction. The previous works on the metabolites of marine fungus Chondrostereum sp. afforded a series of new hirsutane sesquiterpenoids, including chondrosterins A (3)–F and hirsutanol E, together with the known compounds hirsutanols A (4), C, F, arthrosporone and incarnal (5) [1,2,3].Chondrosterin A, hirsutanol A, and …

Hirsutanol a

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WebHirsutanol A is a novel sesquiterpene compound purified from fungus Chondrostereum sp. in Sarcophyton tortuosum [17]. Our previous studies showed that Hirsutanol A exerted

Web15 gen 2024 · Hirsutanol A (61) is an antitumor compound that belongs to hirsutane sesquiterpenes with a linear triquinane skeleton. Compound ( 61 ) was first extracted from the saline fermentation broth of an unidentified sponge-associated fungus (95–1005C) [ 113 ]. Web14 lug 2014 · In the course of our investigation on the secondary metabolites of marine fungi associated with marine organisms in coral reefs, a variety of novel and/or bioactive metabolites were isolated [1,2,3,4,5,6,7].The starfish, Acanthaster planci, is found easily in the coral reef of the South China Sea and is notorious for preying on corals and is …

Web13 giu 2024 · The neurotoxicity of the inhaled anesthetic, sevoflurane, has been documented in a number of studies. In this study, we conducted experiments to investigate whether Hirsutanol A (HA), a sesquiterpene compound from the fungus, Chondrostereum sp., can provide protection from sevoflurane-induced neurological toxicity in aged rats, … Web31 mar 2024 · The natural product veranamine was isolated from the marine sponge Verongula rigida. It contains a unique heterocyclic scaffold and demonstrates in vivo antidepressant activity and selective affinity for 5HT2B and sigma-1 receptors. The first total synthesis of veranamine is reported. Our scalable synthesis offers veranamine in six …

Web31 ago 2011 · Because both optical rotations of 1 and hirsutanol A, a major component from an unidentified fungus, 4 are negative and the 13 C NMR data of 1 are in accord …

WebMar. Drugs 2014, 12 168 Keywords: marine fungus; Chondrostereum sp.; sesquiterpenoids; chondrosterins; cytotoxic activity 1. Introduction The previous works on the metabolites of marine fungus Chondrostereum sp. afforded a series of new hirsutane sesquiterpenoids, including chondrosterins A (3)–F and hirsutanol E, together with the known compounds … prorated serviceWeb13 giu 2024 · The neurotoxicity of the inhaled anesthetic, sevoflurane, has been documented in a number of studies. In this study, we conducted experiments to … prorated sentenceWeb7 gen 2014 · Hirsutanol A is a sesquiterpenoid compound extracted from marine organisms and its antitumor activity is widely recognized (29,30). At present, ... rescare winchesterWeb1 lug 2010 · Hirsutanol A significantly inhibited proliferation of Hep3B cells with 50% inhibition concentrations (IC50) of 14.54, 6.71, and 3.59 micromol/L when exposed to … rescare winfield ksWebCytotoxic alkaloids from the marine shellfish-associated fungus Aspergillus sp. XBB-4 induced by an amino acid-directed strategy†. Yi Qiu a, Qi Guo a, Yan-Qin Ran b, Wen-Jian Lan c, Chi-Keung Lam a, Gong-Kan Feng d, Rong Deng d, Xiao-Feng Zhu d, Hou-Jin Li * a and Liu-Ping Chen * a a School of Chemistry, Sun Yat-sen University, Guangzhou … rescare winfieldWebBackground and objective: Hirsutanol A is a novel sesquiterpene compound purified from fungus chondrostereum sp in Sarcophyton tortuosum. Its pharmacologic effect has not been reported yet. This study aimed to investigate cytotoxic effect of Hirsutanol A on hepatocellular carcinoma (HCC) cells and its mechanism. rescare wellington ohioWeb1 feb 2011 · A new hirsutane sesquiterpenoid, hirsutanol E (1), together with the known compounds hirsutanol A (2) and hirsutanol F (3; gloeosteretriol) were obtained from AcOEt extract of the marine fungus Chondrostereum sp., which was isolated from the soft coral Sarcophyton tortuosum. The structures were elucidated mainly on the basis of the … prorated service charge