2024 Klf13 cancer

Klf13 cancer

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August undefined, 2024

WebPost-transcriptional suppression of KLF13 by miR- 125-5p results in the inhibition of osteosarcoma cells. Nonetheless, overexpression of KLF13 could abolish the tumor-suppressive effects of miR-125-5p. Taken together, these results suggest the tumor-suppressiveroleofmiR-125-5pinandpointtowarditstherapeuticpotentialinthetreatment … WebFeb 22, 2024 · KLF13 is predominantly expressed in heart, interacting with GATA-4 and regulating the early stage of cardiogenesis. 3 In the mice model, KLF13 deficiency …

KLF13 SUPPRESSES THE TRANSFORMING ACTIVITY OF K-

WebJan 28, 2024 · The physiological and biochemical characters of muscles derived from pasture-fed or barn-fed black goats were detected, and RNA-seq was performed to reveal the underlying molecular mechanisms to identify how the pasture feeding affected the nutrition and flavor of the meat. We found that the branched chain amino acids, unsaturated fatty … WebNov 8, 2024 · In addition, PEBP1P2 increased KLF13 mRNA levels by acting as a sponge for miR-296, miR-616, and miR-3194. PEBP1P2 inhibits ccRCC metastasis formation and regulates both PEBP1 and KLF13. ... renal cell carcinoma (RCC), accounts for 4% of all cancer cases worldwide [1,2,3]. In recent years, smoking, alcohol consumption, and … my hero world heroes mission free

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WebFor instance, KLF13 regulates the life cycle of human papillomavirus in cervical keratinocytes, 38 and KLF13 significantly suppresses cell proliferation and induces apoptosis in pancreatic cancer cells. 39 In addition, KLF13 has been confirmed to inhibit the EMT process of pancreatic cancer cells and suppress the invasion and migration of ... WebTaken together, downregulation of KLF13 was observed in fibrotic human/mouse kidneys, and its negative correlation with fibrogenic ECM protein genes suggested a potential role of KLF13 in the pathogenesis of kidney fibrosis. KLF13 inhibits TGF-β signaling by trans-repression in renal TECs WebAs a suppressive transcription factor, KLF13 has been found to be involved in some cell processes of several cancer types. KLF13 expression was inhibited in prostate cancer while its... my hero worksheet

Expression of KLF13 in cancer - Summary - The Human …

MicroRNA-125-5p targets Kruppel-like factor 13 (KLF13) to …

WebJan 4, 2024 · CDK13 interacts with E2F5 in PCa cells. a, Co-immunoprecipitation coupled with mass spectrometry (CoIP-MS) was performed with an anti-CDK13 in PC3 cells to detect the proteins interacting with CDK13, which are shown on the right panel. b, Heat map showing the differential expression (fold changes) of mRNAs between PCa and BPH … WebNov 6, 2024 · Zinc protein KLF13 is a tumor-suppressive member of Kruppel-like factors family, and yet the effect of KLF13 on gastric cancer has not been reported. Here, we … my hero world heroes mission digital releaseWebJan 22, 2024 · In a carcinogen-induced murine lung cancer model, multiplex IHC confirmed that LRRK2 was expressed in alveolar type II (AT2) cells, a main LUAD cell-of-origin, while its loss perturbed AT2 cell ... my hero world heroes dub

"WebKLF13 Gene, Drug Resistance, Tissue Distribution, Mutation Distribution, Variants, KLF13 Genome Browser, KLF13 References KLF13 - Explore an overview of KLF13, with a … " - Klf13 cancer

Klf13 cancer

CDK13 upregulation-induced formation of the positive feedback …

WebKLF13 is known for its tumor promotive role and has been shown to affect cell differentiation, proliferation, cell cycle and apoptosis (Wu et al. 2024 ). The present study showed that miR-125 has sufficient downregulation in osteosarcoma and directly targets KLF13 to regulate the growth and viability of osteosarcoma cells. WebJun 1, 2010 · KLF13 is a transcription factor required for the expression of several oncogenes. FGFR3 is a fibroblast growth factor receptor that initiates a signaling cascade leading to the activation of...

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WebKLF13 (BTEB3, FKLF-2, NSLP1, RFLAT-1) protein expression summary. ... Prognostic marker in renal cancer (favorable) Renal cancer p0.001. Cancer specificity i Low cancer specificity: Cell line expression cluster i. Myeloma - Humoral immune response (mainly) Cell ... WebKLF13 PATHOLOGY CANCER Dictionary Human pathology PROGNOSTIC SUMMARYi Prognostic marker in renal cancer (favorable) Renal cancer p<0.001 RNA EXPRESSION …

WebJun 1, 2007 · In contrast, inducing CCL5 expression may be therapeutic for cancer and AIDS. CCL5 is ubiquitously expressed in a variety of tissues under different conditions (20-23). In fibroblasts, epithelial cells, ... KLF13 is the major transcription factor regulating CCL5 expression in T lymphocytes (27, 28). KLF13 is expressed late (days 3–5) ... WebAug 23, 2012 · KLF13 is coimmunoprecipitated with anti-Flag Ab (Fbw7), and Fbw7 coimmunoprecipitates with anti-T7 Ab (KLF13; Figure 3B), showing that KLF13 is …

WebMay 21, 2024 · Gene expression profiling predicts a role for KLF13 in clofoctol-mediated inhibition. To address the mechanisms by which clofoctol suppresses growth of GSCs, we performed gene expression profiling using mRNA microarray analysis. GSC2 cells were incubated with 1% DMSO or clofoctol at 3 μM and 10 μM for 6 hours before RNA was … WebMay 14, 2024 · As a suppressive transcription factor, KLF13 has been found to be involved in some cell processes of several cancer types. KLF13 expression was inhibited in prostate cancer while its...

WebNov 6, 2024 · Zinc protein KLF13 is a tumor-suppressive member of Kruppel-like factors family, and yet the effect of KLF13 on gastric cancer has not been reported. Here, we …

WebOct 20, 2016 · Expression of KLF13 in normal cervical epithelium is low but increases significantly in cervical intraepithelial neoplasia and invasive squamous cervical cancer. After HPV infection, the E7 protein suppresses ubiquitin ligase FBW7 expression leading to an increase in KLF13 expression. ohio ninth circuit court of appealsWeb开馆时间：周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 my hero wood heroWebSep 24, 2013 · KLF2, KLF3, KLF4, KLF11, KLF13, KLF14, KLF15 and KLF16 all inhibit cell growth and transformation mediated by oncogenic KRAS 85. However, in mouse … my hero world heroes mission dvd release dateWeb来源：CANCER-AM CANCER SOC( P 0008-543X E 1097-0142 ) 发表时间: 2024/02. ... 4 Transcription factor KLF13 inhibits AKT activation and suppresses the growth of prostate carcinoma c.. 来源：CANCER BIOMARK( P 1574-0153 E 1875-8592 ) 发表时间: 2024/01. ohio nmsdcWebJan 1, 2024 · For instance, Zhang et al. revealed that human papillomavirus (HPV) infection increased KLF13 expression and that KLF13 is critical for the activation of HPV productive life cycle, which suggest the involvement of KLF13 in cervical cancer initiation and progression (Zhang et al., 2016). ohio nissan manufacturing facilityWebNov 11, 2013 · A number of KLFs can influence transcriptional networks involved in the control of cancer cell invasion ( 11 ), apoptosis ( 11 ), proliferation ( 12) and the maintenance of CSC ( 13 ). In endometrial cancers, the transcript levels of KLF9 were downregulated, and the levels of KLF13 were upregulated relative to normal endometrium ( 14 ). ohio nonbusiness incomeWebApr 4, 2024 · KLF13 KLF transcription factor 13 [ (human)] Kruppel-like Factors 3 Regulates Migration and Invasion of Gastric Cancer Cells Through NF-kappaB Pathway. UC-BSCs … ohio no cash bail