Ly49 family
WebRequest Bulk Quote. Description. Ly49H, also known as Cmv1 and Klra8, is a 28.3 kD protein. It is expressed on NK cells (but not on NKT cells) from C57BL/6 mice (but not … WebClone 14B11 recognizes a common epitope of the mouse Ly-49C/F/I/H family members which are single-pass type II C-type lectin-like membrane glycoproteins, also known as …
Ly49 family
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Web1 iul. 2001 · The mouse lectin‐related Ly49 family provides a useful model system to study the role of this class of receptors in the regulation of the immune system, and a review summarizes the current members of the Ly49 gene family, their MHC class I recognition and associated signal transduction pathways. Summary: The mouse lectin‐related Ly49 … WebThe A1 monoclonal antibody specifically binds to the Ly-49A[B6] alloantigen, an inhibitory receptor that is expressed on subsets of natural killer (NK) cells and NK-1.1-positive T lymphocytes (NKT cells) in C57BL/6, C57BL/10, and B10 congenic mice, on a population of memory CD8+ T lymphocytes and NK1.1+ γδ T cells in C57BL/6 mice, and on a distinct …
Webmurine Ly49 family, and the NKG2/CD94 receptors (present in both species) (3, 4). Additional immune receptors such as the leu-kocyte Ig-like receptors (LILR, also known …
WebSynergized regulation of NK cell education by NKG2A and specific Ly49 family members. Nature communications. Zhang X,Feng J,Chen S,Yang H,Dong Z. 12-5895-82 was used in Flow Cytometry to provide genetic evidence supporting that NKG2A and the inhibitory members of Ly49 family receptors synergize to regulate NK cell education. Web21 mar. 2024 · Aliases for KLRA1P Gene. GeneCards Symbol: KLRA1P 2. Killer Cell Lectin Like Receptor A1, Pseudogene 2 3 5. LY49L 2 3 5. Ly49 2 3 5. Killer Cell Lectin-Like …
Weba Diagram of Ly49-family genes in the NKC locus. Blue filled arrows denote inhibitory receptors and red filled arrows denote activating receptors. Scissors represent CRISPR …
Web18 iul. 2016 · Ly49 molecules also show specificity for specific MHC alleles. Genomes of humans and other primates contain a single Ly49-like gene. This is a pseudogene in … how many households in indiaWeb13 nov. 2007 · In addition to the Ly49 family expression, we found decreased expression of NK cell maturation markers such as Mac-1 and CD43 in Runx dn-Tg mice . We cannot … how many households in michiganLy49 is a family of membrane C-type lectin-like receptors expressed mainly on NK cells but also on other immune cells (some CD8+ and CD3+ T lymphocytes, intestinal epithelial lymphocytes (IELs), NKT cells, uterine NK cells (uNK) cells, macrophages or dendritic cells). Their primary role is to bind MHC-I … Vedeți mai multe Role in NK cells The function of NK cells is the killing of virally infected or cancerous cells. Therefore, they must have a precisely regulated system of self-cell recognition to prevent the … Vedeți mai multe Inhibitory receptors Inhibitory receptors play a role in the NK cell licensing and are important for recognition and tolerance of self cells. Stimulation … Vedeți mai multe howard altman easton paWeb4 dec. 2012 · The Nkrp1 (Klrb1)-Clr (Clec2) genes encode a receptor-ligand system utilized by NK cells as an MHC-independent immunosurveillance strategy for innate immune responses. The related Ly49 family of MHC-I receptors displays extreme allelic polymorphism and haplotype plasticity. In contrast, previous BAC-mapping and aCGH … howard alumni apparelWeb1 nov. 2024 · Ly49 family is dispensable for NK-cell development. a Diagram of Ly49-family genes in the NKC locus. Blue filled arrows denote inhibitory receptors and red … howard altman urologistWebPurified anti-mouse Ly49D Antibody - Ly49D is a type II transmembrane protein belonging to the Ly49 family of NK-cell receptors in the C-type lectin superfamily. Ly49D is … how many households in maineWebThe monoclonal antibody 14B11 reacts with murine Ly49C, Ly49F, Ly49H, and Ly49I, members of the lectin-like homodimeric Ly49 family of cell surface receptors. Mouse … howard altman business manager