Overduplication
WebJul 15, 2016 · We further find that Cep78 is required for Plk4-induced centriole overduplication and for re-duplication in aphidicolin-arrested U2OS cells. Upon depletion … WebSynonyms for DUPLICATION: duplicate, image, twin, clone, replica, picture, double, counterpart; Antonyms of DUPLICATION: reverse, opposite, antithesis, converse ...
Overduplication
Did you know?
Web维普中文期刊服务平台，是重庆维普资讯有限公司标准化产品之一，本平台以《中文科技期刊数据库》为数据基础，通过对国内出版发行的15000余种科技期刊、7000万篇期刊全文进行内容组织和引文分析，为高校图书馆、情报所、科研机构及企业用户提供一站式文献服务。 WebSep 1, 2024 · Accordingly, centrosome overduplication must depend on other oncogenic changes but require p15 and p16 loss. Interplay between the CDKN2 proteins and other …
WebCENATAC is an essential gene whose product has previously been reported to interact with pre-mRNA splicing factors and to localize to centrosomes where it suppresses centriole … WebFeb 10, 2024 · Centriole overduplication gives rise to a higher number of daughter centrioles than of mother centrioles, whereas centriole accumulation gives rise to an equal number …
WebSep 22, 2010 · Experimentally, centrosome overduplication can be induced in certain cell types by treatment with drugs, such as hydroxyurea, that inhibit DNA synthesis and … WebFeb 14, 2024 · Centrosome amplification—the presence of supernumerary centrosomes—has therefore been proposed to occur by two main routes, overduplication, …
Web摘要 背景与目的:力达霉素(lidamycin,LDM,又称C鄄1027)是一种新型的具有烯二炔结构的抗肿瘤抗生素,在体内外对肿瘤具有显著抑制作用。 本研究旨在观察力达霉素对小鼠结肠癌26皮下、盲肠、肝内、脾内移植瘤以及肝转移瘤的抑制作用。方法:小鼠结肠癌26移植于小鼠皮下、盲肠浆膜下(原位移植)、肝内等 ...
WebJan 21, 2009 · 1. Extra centrosomes and Cancer. Centrosome amplification (supernumerary centrosomes) is a common characteristic of most solid and hematological cancers … open an etoro accountWebBRCA1 is a DNA damage response protein and functions in the nucleus to stimulate DNA repair and at the centrosome to inhibit centrosome overduplication in response to DNA … open an etsy shop canadaWebApr 12, 2024 · PDF On Apr 12, 2024, Xing Bian and others published Corrigendum: The MYC paralog-PARP1 axis as a potential therapeutic target in MYC paralog-activated small cell … open a new bank account offersWebOct 21, 2010 · Centrosome overduplication is associated with elevated cyclin E/Cdk2 activity in other cell types; loss of p53, which can inhibit cyclin E accumulation, also promotes … open a new account with natwestWebDec 9, 2011 · The aberrant cyclin A expression subsequently induced centrosome overduplication, and this effect was abolished by calpain-specific inhibitors or RNA … iowa headline newsWebExperimentally, centrosome overduplication is observed in p53-deficient cells arrested in S phase with hydroxyurea. Using this assay, we have identified distinct roles for Cdk2, … open an etsy account to sellWebJan 19, 2024 · Dedicated, motivated and ambitious. A great passion for science.Fascinated with problem solving, trouble shooting and developing new techniques.A positive thinker, … iowa head start