WebApr 12, 2024 · Postoperative neurocognitive dysfunction (PND) is a common postoperative complication. Autophagy is correlated with the pathogenesis of PND. This study investigated the potential role of autophagy in the neuroprotection of Dexmedetomidine (Dex) pretreatment in PND. The PND rat model was established by abdominal surgery. … WebApr 12, 2024 · AbstractRecent studies have shown that autophagy plays an important role in gynecologic tumors, and ubiquitin modification of autophagy regulatory components is essential to regulate autophagic flux. In this study, we found that the ubiquitin-conjugating enzyme E2C (UBE2C) affects endometrial cancer cell apoptosis and proliferation by …
Autophagy and Metabolism - PMC - National Center for …
WebBased on this premise, this narrative literature review aimed to investigate the possible connection between 1,25D3 and autophagy in periodontitis. A comprehensive literature search was conducted on PubMed using the following keywords (e.g., vitamin D, autophagy, periodontitis, pathogens, epithelial cells, immunity, inflammation, and bone loss). WebSep 24, 2015 · This causes a lysosomal stress response. Aneuploid cells activate the transcription factor TFEB, a master regulator of autophagic and lysosomal gene expression, thereby increasing the expression of genes needed for … buy butane cartridge
Small molecule probes for targeting autophagy - Nature
WebMay 8, 2024 · In order to investigate whether the autophagy is altered in response to SARS-CoV-2 infection, we infected GFP-LC3 transfected Vero-E6 cells at MOI of 0.05. WebApr 3, 2024 · We further revealed that the loss of AKT1 was the reason for the increased autophagy level of DDP resistant ovarian cancer cells. Our study provides new insights into reversing DDP resistance in ovarian cancer by targeting ferroptosis pathway, and AKT1 may be a molecular marker of susceptibility to ferroptosis. WebOct 1, 2024 · Canonical autophagy is a multiphasic process that involves the sequential and selective recruitment of ATG (autophagy related) proteins (Galluzzi et al, 2024a).The … celine mahe tours